The first two weeks of my internship at the Wasserman Lab have been an exciting and new experience. From learning about a multitude of rare genetic diseases to determining the sex of subjects from genetic data, every day at the lab is packed with new experiences, challenges and opportunities. The Wasserman Lab is based out of BC Children’s Hospital, performing genome and exome analysis for children with rare, undiagnosed genetic diseases. My main task this month is to help update their patient database. I also had the opportunity to work with test cases and to learn how to use different databases, tools and programs in order to retrieve information.
Today I was taught how to create candidate variant lists, which are basically lists of the different mutations that could be responsible for a certain genetic disease in a patient. I also continued to work on the test cases I was assigned, where I am attempting to find the genes responsible for different diseases. It is really cool to learn about the genes and diseases they are associated with as I have never heard of almost any of them. This process has opened my eyes to just how many different and rare diseases there are in the world, something I didn’t quite realize before.
I’m extremely grateful for this opportunity to work in a lab that does such fascinating research, and to work with such a supportive and helpful supervisor. I’m looking forward to the next coming weeks!